Scientists at the Zurich Federal Institute of Technology have found a great opportunity to create biocomputers using a human cell to develop a two-core bioprocessor.
According to the information reported, this biocomputer is based on a genetic editing technique that serves the CRISPR-Cas9 registry, working with reprogrammable processor cores.
The researchers explain that the use of human cells helps to take advantage of metabolic computational capacity, taking into account that they can process up to 100,000 different metabolic molecules and each acts as a gateway to the processor. The necessary power is generated through a special variant of the Cas9 protein responsible for forming the processor core.
The central processing unit is able to regulate the expression of a specific gene using the input provided by the guiding RNA sequence. Based on this process, it is possible to program scalable circuits in human cells without the need to develop a processor for each assignment.
Thanks to these steps, scientists are able to use CRISPR-Cas9 components from two different bacteria to create a dual-core biological processor similar to what we see in electronic devices. The team’s next goal is to create a multi-core bioprocessor within a single cell.